A massive global study has found that nearly 40% of all new cancer cases worldwide are linked to modifiable risk factors and are therefore potentially preventable.

This comprehensive investigation, which analyzed data across 185 countries, reveals that in 2022, approximately 7.1 million of the 18.7 million new cancer diagnoses were attributable to avoidable causes.

The findings pinpoint two habits as major drivers: tobacco smoking was the single leading contributor, followed by infections and alcohol consumption.

“This landmark study provides staggering evidence for what we in the oncology community have long advocated: a significant portion of the cancer burden is preventable,” said Dr. Rosario Ligresti, Chief of Gastroenterology at Hackensack Meridian Hackensack University Medical Center. “While we are equipped with cutting-edge treatments for patients, this research powerfully reinforces that the first line of defense against cancer often begins with personal choices. It’s a crucial message of empowerment—that quitting smoking and moderating alcohol use are not just healthy habits, but life-saving actions that can dramatically reduce one’s risk of ever needing our services.”