Darline Graham Nordone, the sister of the late Sen. Lindsey Graham, has been selected to temporarily fill his U.S. Senate seat, with South Carolina Gov. Henry McMaster announcing Monday that she will serve until the current term expires in January.

Speaking at a Statehouse news conference, McMaster said Nordone would complete the remainder of her brother’s term. A source familiar with the appointment, who was not authorized to discuss the matter publicly, said she is expected to be sworn into office on Wednesday. Her appointment will make her the first woman ever to represent South Carolina in the U.S. Senate.

“It is such an honor,” Nordone said. “Lindsey has always been there for me. And now, I will be there for him.”

Graham, who died over the weekend at the age of 71, never married and had no children. Throughout his political career, however, Nordone remained one of his closest confidantes, frequently accompanying him to major campaign events and even appearing in campaign advertisements.

The siblings shared an especially close bond dating back to their youth. After the death of their parents, Graham assumed responsibility for raising his younger sister and later became her legal guardian. Earlier this year, she stood beside him—joined by her children and grandchildren—as he officially filed paperwork for what would have been his reelection campaign.

Voters will head to the polls next month to choose the Republican nominee for the special election to fill Graham’s seat. Before his death, Graham had been seeking a fifth term in the Senate.

The unexpected vacancy has immediately set off intense maneuvering among South Carolina Republicans, with several high-profile conservatives now considering bids for the coveted Senate seat.

The race comes just after Republicans concluded a hard-fought gubernatorial primary. State Attorney General Alan Wilson emerged as the nominee after defeating a crowded field that included Lt. Gov. Pamela Evette, Rep. Nancy Mace, and Rep. Ralph Norman. In the wake of Graham’s death, several of those same figures are now weighing Senate campaigns.

Under South Carolina law, candidates will have one week to file for the special Republican primary beginning on July 21, the second Tuesday following Graham’s death.

The special primary is scheduled for Aug. 11, with a runoff, if necessary, slated for Aug. 25.

Whoever captures the nomination will then have just over two months to campaign before the Nov. 3 general election.

The accelerated election calendar could create legal complications because federal law requires military and overseas absentee ballots to be distributed at least 45 days before a federal election. For the special primary, that deadline would already have passed on June 27. Federal election officials did not immediately clarify how that conflict would be addressed.

Graham died Saturday evening. According to a preliminary report from the medical examiner, the cause of death was an aortic dissection, a tear in the wall of the aorta.

Within hours of the announcement of his death, speculation was already swirling throughout South Carolina Republican circles over who might ultimately succeed him. Because the general election is so close, McMaster’s appointee could enjoy an advantage heading into the special primary, although it is also possible the governor intended the appointment simply as a temporary caretaker.

One frequently mentioned possibility had been Lt. Gov. Pamela Evette, who has served alongside McMaster for nearly eight years and received his endorsement in this year’s gubernatorial race before losing the June 23 runoff to Alan Wilson.

A source familiar with Evette’s thinking said she has been encouraged by supporters across the state and believes she would be a strong contender in the special primary.

Political observers believe it is unlikely that a sitting member of the U.S. House would be appointed to finish Graham’s current term because Republicans hold only a narrow majority in the House of Representatives.

Rep. Joe Wilson, whose name surfaced as a possible replacement, said he assured President Trump on Sunday that “my goal is to remain in the House to keep his two-vote majority for the American people!!!”

That does not rule out House members seeking the full Senate term. A person familiar with Rep. Nancy Mace’s deliberations said she is seriously considering entering the race. Mace is not seeking another term in the House.

Another Republican whose name has surfaced is Rep. Russell Fry, a two-term congressman representing the rapidly growing Myrtle Beach region who has become one of President Trump’s strongest allies in Congress.

Businessman Mark Lynch, who unsuccessfully challenged Graham in the Republican primary, is also viewed as a potential candidate. In addition, sources close to former South Carolina Gov. Mark Sanford said he is weighing whether to enter the race.

Treasury Secretary Scott Bessent, who lived in South Carolina before joining the Trump administration, has also received inquiries about the Senate seat. However, according to a person familiar with private discussions, Bessent has no interest in running and is content serving in the administration.

Although Democrats have struggled to win statewide races in South Carolina for decades, Republicans are treating the contest seriously despite the state’s strong GOP advantage. Graham won reelection in 2020 by defeating Democrat Jaime Harrison by 10 percentage points.

While history suggests Republicans remain favored to retain the seat, party leaders continue to assess what is shaping up to be a highly competitive primary.

On the Democratic side, Charleston pediatrician Annie Andrews secured her party’s nomination last month. Federal campaign filings show she has raised more than $8 million and had nearly $3 million in cash available at the end of May. Graham’s campaign had raised approximately $6 million and held just over $4 million before his death.

In a statement issued Sunday, Andrews urged South Carolinians to join her “in setting partisanship aside and offering gratitude” to Graham for his years of public service.

Jaime Harrison, Graham’s Democratic opponent in 2020, also paid tribute, writing on social media that although he and Graham “had our share of political disagreements,” he “always appreciated that even in our fiercest political battles, we could still share a conversation, a laugh, and a mutual respect for South Carolina and the institutions we were both privileged to serve.”

Graham’s passing also leaves a significant leadership void in the Senate, where more than two decades of service had given him substantial influence over committees and legislative priorities.

South Carolina’s other senator, Tim Scott, has served since 2012, far less time than many of the state’s longtime Senate figures such as Fritz Hollings, who served 38 years, and Strom Thurmond, whose tenure lasted 47 years.

Scott, who co-chaired Graham’s reelection campaign, called his longtime colleague “irreplaceable.”

“America lost a statesman, but I lost a friend,” he told ABC’s “This Week.”