Former New York City Mayor Rudy Giuliani came out of a coma Monday and was awake and speaking while continuing treatment in a Florida hospital after battling pneumonia, longtime friend John Catsimatidis told reporters.

Catsimatidis said he received the update Monday afternoon from a close former aide to the 81-year-old. “He’s talking, he’s alert. To me, that’s great news,’’ the supermarket and media mogul told reporters.

Giuliani was hospitalized over the weekend after falling ill with a serious respiratory infection, his business partner Tom von Essen – the city’s fire commissioner during 9/11 – said.

“Rudy had a tough weekend. He had pneumonia,” von Essen told The NY Post, describing Monday as “an important day’’ in terms of Giuliani’s recovery.

A spokesman for Giuliani, Ted Goodman, confirmed to the Post the former mayor was recovering from pneumonia and remained under observation as a precaution.

He is now breathing independently, with family members and his primary doctor by his side, the spokesman said.

“Mayor Giuliani is the ultimate fighter – as he has demonstrated throughout his life – and he is winning this battle,” Goodman said.

The illness is linked to a chronic condition tied to Giuliani’s exposure during the Sept. 11, 2001 terror attacks, his representative added.

“On September 11th, Mayor Giuliani ran toward the towers to help those in need, which led to a restrictive airway disease diagnosis,” the spokesman said.

“This disease adds complications to any emerging respiratory issue, and the virus quickly overwhelmed his body, requiring mechanical ventilation to maintain his blood pressure.”

The latest update followed Sunday’s disclosure that Giuliani – a close ally of President Trump – was in critical but stable condition with an unspecified illness at the time.

Messages of support poured in, including from New York City Mayor Zohran Mamdani.

“Absolutely, I’m wishing strength and recovery to former Mayor Rudy Giuliani and his loved ones during this difficult time. And I hope that his recovery is steady, and I hope that his family finds peace in one another during this time,” Mamdani said during a press conference.

“I think former Mayor Giuliani is someone that we, as New Yorkers, know well, and he’s been a fixture in our city’s politics and public life for so many years, and I know that many New Yorkers are concerned by reports he is in critical condition and so we do keep him and his family in our prayers at this time,” he added.

Former New York Gov. George Pataki told the Post he had been expecting to see Giuliani at a charity event later in the week.

“I was looking forward to seeing him … and being able to talk at length,’’ Pataki said. “I haven’t talked to him in a few months.

“We were great partners for the city and the state for seven years together, and we were able to just do a tremendous amount to make the city and state a better place by working together.

“So obviously now we just hope he gets better,’’ Pataki said.

Pataki said he was stunned to learn Giuliani had been hospitalized.

“It was just a shock’’ to learn Giuliani was even hospitalized, he said.

“You just take for granted that figures that have such a large profile in our state and our country will be around for a long time,’’ he added.

At the same media gathering, WABC host Dominic Carter also expressed support, saying, “History is going to judge [Giuliani] as the greatest mayor of New York City ever.”

Asked about their long friendship – despite past legal disputes – Catsimatidis said the bond remains strong.

“Friends for 40 years, brothers for 40 years,’’ he said.