FLUSHING, N.Y. — Four people, including a child, were killed Monday in a four-alarm fire at a mixed-use building in Queens that also injured firefighters and forced some residents to jump to escape the flames, officials said.

The blaze broke out shortly before 12:30 p.m. at 44-49 College Point Boulevard in the Flushing neighborhood, according to the New York City Fire Department. The building contained businesses on the ground floor and apartments above.

Just before 12:30 Monday afternoon, the FDNY responded to a 4-alarm fire at 44-49 College Point Boulevard in Queens. Tragically, four people lost their lives in this fire. Two other victims were transported to area hospitals in critical condition.

During operations, a… pic.twitter.com/mX6W0WnPoR

— FDNY (@FDNY) March 16, 2026

Firefighters arriving at the scene encountered heavy fire on all three floors. During the response, a victim trapped on the second floor was rescued using a portable ladder, officials said.

As crews advanced inside, a stairwell collapsed, trapping two firefighters. They were later extricated and taken to area hospitals in stable condition.

Three victims, including a child, were found dead inside the building. A fourth person who had been transported to a hospital in critical condition later died, officials said. Two additional victims were taken to hospitals in critical condition, and several others were treated at the scene.

More than 230 firefighters and emergency medical personnel responded to the fire. Officials said firefighters also performed CPR on victims outside the building as rescue efforts continued.

“This is a difficult and tragic day,” said Lillian Bonsignore. “The Fire Department did an extraordinary job under difficult circumstances, putting this fire out and saving people.”

The fire was brought under control shortly before 2:45 p.m., officials said. Fire marshals are investigating the cause.

We’re mourning the loss of four New Yorkers after today’s devastating four-alarm fire in Flushing. My heart is with their families, loved ones and every neighbor impacted.

Thank you to the FDNY firefighters and EMS workers who rushed in within minutes, risking their lives to…

— Mayor Zohran Kwame Mamdani (@NYCMayor) March 16, 2026

Mayor Zohran Kwame Mamdani expressed condolences to the victims’ families and praised firefighters and emergency crews who responded to the scene.

UPDATE: Three people have been pronounced dead at Flushing Queens fire this afternoon. https://t.co/0CCMier86X pic.twitter.com/ZsbU3Mo0se

— Oliya Scootercaster 🛴 (@ScooterCasterNY) March 16, 2026

My heart breaks for those we lost in the fire today in Queens.

I’m thankful to @FDNY and our first responders who risk their lives to protect our communities, and I’m praying for a full recovery to those who have been injured.https://t.co/mWtN0lYZM6

— NY AG James (@NewYorkStateAG) March 16, 2026